DKM活性分子 Decode Key Molecules 活性化合物活性分子平台 7*24在线

DKM活性分子 Detect・Discover・Decode Key Molecules —— 活性分子平台 | 7×24 在线 ☎️400-168-1698 📩info@dkm.cn

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Mabs In Vivo

PD-1/PD-L1

Angiogenesis

Apoptosis

Natural product

Cancer

Epigenetics

Stem Cells

ADC Related

DKM活性化合物

神经科学前沿造模剂「疾病诱导模型」简介（含完整实验Protocol）

DKM提供多种疾病模型造模剂，覆盖肿瘤、神经、免疫等多系统，包括PLX5622、Pexidartinib（小胶质清除）、MPTP（帕金森病）、奥沙利铂（CINP）和红藻氨酸（癫痫）等，配套详细方案与验证方法。

DKM活性化合物 5小时前

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Anlotinib (AL3818) dihydrochloride ，安罗替尼，ALTN、 Anlotinib、 Anlotinib Hydrochloride实验方法步骤SOP

本SOP规范盐酸安罗替尼（CAS 1360460-82-7）在细胞实验中的配制与使用，强调禁用PBS、须用生理盐水稀释，提供储备液配制、浓度换算、给药及检测全流程操作要点。再次强调：推荐以生理盐水溶解，禁用PBS，以免引发析出。

DKM活性化合物 7小时前

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攻克不可成药靶点：RAS的华丽转身，化身抗癌利器

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DKM活性化合物 1天前

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细胞因子（Cytokine, CK）：功能解析、作用机理及检测策略（附52 种细胞因子总结表）

细胞因子（cytokine, CK）是免疫系统中关键的信使分子，由免疫及非免疫细胞分泌，具多效性、重叠性等特性，参与抗感染、炎症调控及疾病发生发展。附52 种细胞因子总结表。

DKM活性化合物 3天前

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DKM类器官培养必备小分子试剂清单大集合｜高效实用，值得存档收藏！

小分子化合物因能穿透细胞膜、靶点多样，在类器官培养中广泛用于调控信号通路、抑制凋亡、促进分化与维持功能，显著提升类器官存活率、稳定性和生理相关性。

DKM活性化合物 6天前

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Dextran sulfate sodium salt MW 40000别名：DSS; 葡聚糖硫酸钠盐 Dextran sulfate sodium（DSS，葡聚糖硫酸钠盐，硫酸葡聚糖 CAS号:9011-18-1 AR级别，分子量4万，高纯度）是葡聚糖的聚阴离子衍生物，由葡聚糖和氯磺酸的酯化反应形成，可用于结肠炎和结肠癌模型的构建。

硫酸葡聚糖（CAS 9011-18-1），AR级，分子量约4万，高纯度，现货供应。

DKM活性化合物 1周前

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DKM资讯

全部

PI3K/Akt/mTOR
- Akt
- AMPK
- ATM/ATR
- PI3K
- PDK
- FOXO
- MELK
- mTOR
- GSK-3
- PDK-1
- PI4K
- PIKfyve
- PIN1
- PTEN
- RSK
Epigenetics
- AMPK
- Aurora Kinase
- DNA Methyltransferase/DNA甲基转移酶
- Epigenetic Reader Domain/表观遗传阅读框
- FTO
- HDAC/组蛋白去乙酰化酶
- HES
- HIF
- Histone Acetyltransferase/组蛋白乙酰转移酶
- Histone Demethylase/组蛋白甲基转移酶
- Histone Methyltransferase/组蛋白甲基转移酶
- JAK
- MBD-containing protein
- METTL3
- MicroRNA/微RNA
- PAD
- PARP
- Pim
- PKC
- PRMT
- SF3B1
- Sirtuin
- TET
- BET
Methylation/甲基化
- PRMT
- EZH2
- DNA Methyltransferase
- LSD1
- MLL
- G9a/GLP
- JMJD
- NSD
- FTO
- SETD
- DOT1
- MAT2A
- SMYD
- COMT
- WDR5
- NNMT
- HNMT
- SAM MTase
- PPMTase
Immunology & Inflammation/免疫炎症
- AIM2
- AP-1
- Arginase/精氨酸酶
- Calcineurin
- CCR
- CD19
- CD2
- CD20
- CD22
- CD276/B7-H3
- CD28
- CD28-B7
- CD3
- CD38
- CD47
- CD6
- CD73
- CD74
- CD80
- cGAS
- Complement C3
- Complement Receptor
- Complement System/补体系统
- COX/环氧化酶
- CRTH2
- CTLA-4
- CXCR
- Cyclophilin
- FAP
- FKBP
- FLAP
- FPR
- Galectin/半乳糖凝集素
- Glucocorticoid Receptor/糖皮质激素受体
- Glycoprotein VI
- GM-CSF
- Histamine Receptor/组胺受体
- HMGB
- IFNAR/干扰素受体
- IKZF Family
- IL Receptor
- others
- IRAK
- IRF3
- LAG-3
- LanC-like protein
- Legumain
- LTA4H
- LTR
- MALT1
- Mesothelin
- MIF
- Mucin
- MyD88
- NADPH Oxidase/NADPH氧化酶
- NFAT
- NLR
- NO Synthesis
- NOS
- NOT
- Nrf2
- PD-1/PD-L1
- PG Synthase
- PSMA
- Pyroptosis/焦亡
- ROS
- S100A9
- Scavenger receptor
- SIK
- SOD
- SphK
- STING
- TENT
- Thrombopoietin Receptor/血小板生成素受体
- Tim3
- TLR
- TSPO
- VISTA
- XBP1
Protein Tyrosine Kinase/PTK酪氨酸蛋白激酶
- EGFR
- VEGFR
- PDGFR
- FGFR
- FLT3
- c-Kit
- Src
- c-Met
- Bcr-Abl
- BTK
- MEK
- HER2
- ALK
- IGF-1R
- CSF-1R
- Trk receptor
- Syk
- c-RET
- FAK
- Axl
- Mertk
- DYRK
- ROS1
- Tyro3
- Pyk2
- RON
- Ephrin receptor
- DDR
- Tie-2
- ACK
- Insulin Receptor
- Fer kinase
Angiogenesis
- EGFR
- VEGFR
- JAK
- PDGFR
- FGFR
- Src
- FLT
- FLT3
- HER2
- HIF
- Bcr-Abl
- BTK
- ALK
- Syk
- FAK
- Hck
- VDA
- ANGPTL
Apoptosis/凋亡
- Apoptosis related/凋亡相关
- Ras
- STAT
- TNF-alpha
- Bcl-2
- Caspase
- K-Ras
- Ferroptosis
- p53
- RIP kinase
- c-RET
- MDM
- MRP
- Antifolate
- Myc
- IAP
- OXPHOS
- PD-1/PD-L1
- FKBP
- PERK
- ABC Transporter
- Thymidylate Synthase
- Heme Oxygenase
- Photosensitizer
- Pyroptosis
- Annexin A
- Survivin
- Disulfidptosis
- ASK
- PFKFB
- DAPK
- Cuproptosis
- Nur77
- Bcl-6
- PKD
- NEDD8
- Necroptosis
- TACE
- FDX1
- Fas/FasL
- cytohesin
- TRADD
- SMARCA2
- ADAM10
Autophagy/自噬
- Autophagy
- Mitophagy
- Nrf2
- CXCR
- LRRK2
- ULK
- FKBP
- Heme Oxygenase
- cGAS
- Cell wall
- LC3
- GluCls
- OGA
- Beclin
- ATTECs
ER stress & UPR/内质网应激&UPR响应
- Antioxidant
- ROS
- HSP
- JNK
- eIF
- PERK
- IRE1
- ASK
- PKR
- PDI
- ER stress
- ATF-6
JAK/STAT
- EGFR
- STAT
- Pim
- JAK1
- JAK2
- JAK3
- Tyk2
MAPK
- Ras
- ERK
- p38 MAPK
- K-Ras
- Raf
- JNK
- MEK
- S6 Kinase
- MAP4K
- Mixed Lineage Kinase
- TAK1
- MAPKAPK2
- ASK
- MNK
- TOPK
- KLF
- p53
Cytoskeletal Signaling细胞骨架
- Akt
- Microtubule Associated
- Wnt/beta-catenin
- PKC
- HSP
- Bcr-Abl
- Integrin
- FAK
- ROCK
- Kinesin
- PAK
- Actin
- MLCK
- Dynamin
- MPS1
- PORCN
- KSP
- Gap-Junction
- Cardiac Myosin
- TACC3
- Piezo Channel
- Myosin
- Tight Junction Protein
Cell Cycle细胞周期
- DNA/RNA Synthesis
- CDK
- Ras
- Microtubule Associated
- K-Ras
- HSP
- Aurora Kinase
- Casein Kinase
- Serine/threonin kinase
- Rho
- ROCK
- Chk
- Kinesin
- PLK
- Myc
- DHFR
- eIF
- PD-1/PD-L1
- PAK
- PERK
- DYRK
- AP-1
- MPS1
- p21
- Wee1
- RUNX
- LIM kinase
- BMI-1
- PP2A
- Nur77
- PFKFB
- TOPK
- Cell Cycle Arrest
- Haspin Kinase
- DOCK
- TACC3
- CDK4/6
- APC
- FOXM1
- Cyclin
- Choline kinase
- Mad2
- KRas inhibitor
TGF-beta/Smad
- PKC
- TGF-beta/Smad
- Bcr-Abl
- ROCK
DNA Damage/DNA Repair/DNA损伤/修复
- DNA/RNA Synthesis
- HDAC
- Topoisomerase
- PPAR
- PARP
- Sirtuin
- Casein Kinase
- ATM/ATR
- MDM
- DNA-PK
- DNA alkylator
- DHFR
- Nucleoside Analog/Antimetabolite
- eIF
- Telomerase
- CRISPR/Cas9
- Thymidylate Synthase
- RAD51
- Alkylating Agent
- RNR
- NUDIX
- BMI-1
- LIM kinase
- OGG1
- MTH1
- G-quadruplex
- High-mobility Group
- FENs
- SMN
- Pax
- WRN
Stem Cells & Wnt/干细胞&Wnt通路
- JAK
- STAT
- ERK
- Wnt/beta-catenin
- TGF-beta/Smad
- GSK-3
- Casein Kinase
- ROCK
- Hedgehog/Smoothened
- PKA
- Notch
- Secretase
- PORCN
- OCT
- KLF
- Fascin
- Stemness kinase
- SFRP
Hippo
- TEAD
- YAP
- MAP4K
- LATS
- MST
Metabolism代谢
- 11β-HSD
- 15-PGDH
- 2OG Oxygenase
- 3-PGDH
- 3MST
- 6PGD
- ACAT
- ACC
- Acetolactate Synthase
- ACMSD
- Aconitate hydratase
- ACS
- Adenosine Deaminase/腺苷脱氨酶
- Adenosylhomocysteinase
- ADP-ribosyltransferase
- AhR
- AKR
- ALDH
- Aldose Reductase/醛糖还原酶
- Aminopeptidase/氨肽酶
- Antifolate/抗叶酸
- AO
- ApoE
- Arginase/精氨酸酶
- Asparagine synthetase
- ATF/CREB proteins
- ATP Citrate Lyase/ATP柠檬酸裂解酶
- BBOX
- BDK
- Beta-glucuronidase
- Carbonic Anhydrase/碳酸酐酶
- Carboxylesterase
- Carboxypeptidase/羧肽酶
- Cardiolipin Peroxidase
- Cathepsin/组织蛋白酶
- Ceramidase/神经酰胺酶
- CETP
- Cholesterol Transporter
- CPA
- CPSI
- Creatine kinase
- Cryptochrome
- CSE
- CYP51
- Cytochrome c oxidase
- D-amino acid oxidase
- D6D
- DAPA synthase
- Decarboxylase/脱羧酶
- Dehydrogenase/脱氢酶
- DGAT
- DGK
- Dopamine β-hydroxylase
- E-NTPDase
- Elastase/弹性蛋白酶
- Enolase/烯醇化酶
- Enteropeptidase
- ERAP
- FABP
- Factor Xa
- Farnesyl Transferase/法尼基转移酶
- FAS
- FBPase/二磷酸酶
- Ferroptosis/铁死亡
- FOXO
- FTO
- Fumarate hydratase
- FVII
- FXR
- G0/G1 switch protein 2
- Galactosidases
- GCN
- GCS
- GGTase
- Glucokinase/葡萄糖激酶
- Glucosidase/葡萄糖苷酶
- GLUT
- Glutaminase C
- Glutathione Reductase
- GOAT
- Glyoxalase
- GPx
- GSNOR
- GST
- Heme Oxygenase (HO)
- Hexokinase/己糖激酶
- HMGCR
- HPSE
- Hydrolase/水解酶
- Hydroxylase/羟化酶
- IDH
- IDO
- Ketohexokinase
- LDL
- LDLR
- Lipase/脂肪酶
- Lipoxygenase/脂氧合酶
- LOX
- LRH-1
- LXR
- MAGL
- MASTL
- MDH
- MetAP
- MGAT
- Mineralocorticoid Receptor/盐皮质激素受体
- Mitochondrial Electron Transport Chain
- Mitochondrial Metabolism/线粒体代谢
- MPC
- NAMPT
- Neprilysin/脑啡肽酶
- NNMT
- NPP
- NPR
- NQO
- OGT
- OPA1
- P448
- P450
- PAI-1
- PARG
- PDE
- PDHK
- PEPCK
- PGAM1
- PGC-1α
- PHGDH
- Phospholipase/磷脂酶
- PI5P4K
- PKM1
- PKM2
- Procollagen C Proteinase
- Proprotein convertases
- Pyruvate Kinase/丙酮酸激酶
- QR
- RAR/RXR
- RBP
- REV-ERB
- ROR
- SCD
- sEH
- SGK
- Sialyltransferase
- SHMT
- SLC25
- Sphingosine acyltransferase
- SQOR
- Srx
- Steroid Sulfatase
- TDO
- TGH
- Thioredoxin/硫氧还蛋白
- Thrombin凝血酶
- Transferase
- Transketolase/转酮酶
- TrxR
- Trypanothione reductase
- UGT
- VD/VDR
- Xanthine Oxidase/黄嘌呤氧化酶
- αKGD
Ubiquitin泛素化
- E3 Ligase
- DUB
- Proteasome
- E1 Activating
- p97
- SUMO
- E2 conjugating
Neuronal Signaling/神经信号
- 5-HT Receptor | 5-羟色胺受体
- AAK1
- AChE
- AChR
- Adenosine Kinase | 腺苷激酶
- Adrenergic Receptor | 肾上腺素能受体
- AMPAR
- Amyloid-β | 淀粉样蛋白-β
- Calcium Channel
- CaMK
- Cannabinoid Receptor | 大麻素受体
- CGRP Receptor | 降钙素基因相关肽受体
- Cholecystokinin Receptor | 缩胆囊素受体
- Cholinesterase
- CHT
- COMT
- DAT
- Dopamine Receptor | 多巴胺受体
- Endorphin
- Enkephalinase
- FAAH
- GABA Receptor | GABA受体
- GABA transporter
- Glucosylceramide Synthase | 葡萄糖神经酰胺合成酶
- GluR
- Glutamate Release
- GPR119
- GPR139
- GPR24
- GPR55
- Histamine Receptor | 组胺受体
- Huntingtin
- Imidazoline Receptor
- Kainate receptor
- MAO
- Melanocortin Receptor | 黑素皮质素受体
- mGluR
- MT Receptor
- NET
- Neuropeptide Y Receptor | 神经肽Y受体
- Neurotensin Receptor | 神经降压素受体
- NGF
- NK Receptor
- NMDA
- NMDAR
- Notch
- Nurr1
- OLIG2
- Opioid Receptor | 阿片受体
- OX Receptor
- P2X Receptor | P2X受体
- PSD-95
- QC
- RAGE
- REST
- Ryanodine Receptor-1
- S100β
- Secretase
- SERT
- Sigma Receptor
- SMS
- SSRIs
- Substance P
- TAAR
- Tau Protein | Tau蛋白
- TLX
- Trk Receptor | Trk受体
- TRP Channel | TRP通道
- TTR
- α-synuclein | α-突触核蛋白
- COX
NF-κB信号通路
- IKK
- MALT1
- NF-κB
- Nrf2
- Pirin
- RANKL
- RANKL/RANK
- RIP kinase | RIP激酶
- TAK1
GPCR & G蛋白
- Adrenergic Receptor
- AChR
- 5-HT Receptor
- Histamine Receptor
- Dopamine Receptor
- Ras
- K-Ras
- GPR
- Prostaglandin Receptor
- GluR
- Adenosine Receptor
- P2 Receptor
- CXCR
- CCR
- Angiotensin Receptor
- S1P Receptor
- Hedgehog/Smoothened
- Cannabinoid Receptor
- PKA
- SGLT
- Opioid Receptor
- cAMP
- Glucagon Receptor
- Sigma Receptor
- PAR
- Endothelin Receptor
- Neurokinin Receptor
- LTR
- LPA Receptor
- PKG
- Guanylate Cyclase
- OX Receptor
- GPCR19
- Platelet aggregation
- GTPase
- Vasopressin Receptor
- CGRP Receptor
- FPR
- Adenylyl Cyclase
- CCK receptor
- MT Receptor
- AdipoR
- PKD
- Taste Receptor
- NPY receptor
- Melanocortin Receptor
- Apelin receptor
- GLP-1 Receptor
- GHSR
- Oxytocin Receptor
- GRK
- CaSR
- Bradykinin Receptor
- Arrestin
- Leukotriene
- DOCK
- Imidazoline Receptor
- TSH Receptor
- TAAR
- Orphan Receptor
- GNRH Receptor
- MCHR
- PAFR
- CRFR
- RXFP receptor
- RGS
Endocrinology & Hormones/内分泌&激素
- 5-alpha Reductase | 5-alpha还原酶
- ACE
- Adrenergic Receptor | 肾上腺素能受体
- Androgen Receptor | 雄激素受体
- Aromatase | 芳香酶
- ERR
- GHSR
- Glucocorticoid Receptor | 糖皮质激素受体
- GNRH Receptor | GNRH受体
- Mineralocorticoid Receptor | 盐皮质激素受体
- Opioid Receptor | 阿片受体
- Progesterone Receptor | 孕酮受体
- PTGR
- PTHR
- Renin
- Sepiapterin reductase
- SSTR
- Taste receptor
- Thyroid Hormone Receptor | 甲状腺激素受体
- TPO
- TRHR
- TSH Receptor | 促甲状腺激素受体
Transmembrane Transporters/跨膜转运
- ABC Transporter
- AKK1
- ANT
- AQP
- AQP3
- ARF
- ATP Synthase | ATP合成酶
- ATPase
- BCRP
- Calcium Channel 钙离子通道
- CFTR
- Chloride Channel | 氯离子通道
- CRAC Channel | CRAC通道
- CRM1
- EAAT
- Efflux pump
- ENT
- Ferroportin
- GABA Receptor | GABA受体
- GLUT
- Glutamate transporter
- Glycine transporter
- HCN Channel | HCN通道
- IBAT
- MAT
- MCT
- Na+/Ca2+ Exchanger
- Na+/K+ ATPase
- Na/HCO3 cotransporter
- NKCC
- Oct
- OCTN
- Organic Anion Transporter
- P-gp
- P2X Receptor | P2X受体
- Piezo
- Potassium Channel | 钾通道
- Proton Pump | 质子泵
- SEO1
- SGLT
- SLC
- Sodium Channel | 钠通道
- SV2
- TRP Channel | TRP通道
- UCP
- URAT1
- Urea Transporter
- VDAC
- VRAC
Proteases蛋白酶
- HDAC
- Caspase
- MMP
- HCV Protease
- Cysteine Protease
- HIV Protease
- Tyrosinase
- DPP
- Proteasome
- Serine Protease
- Secretase
- Acyltransferase
- Glutaminase
- Thrombin
- Cathepsin B
- PCSK9
- Carboxypeptidase
- PREP
- PAD
- Neprilysin
- SGK
- MALT
- Aminopeptidase
- 3C-Like Protease
- GOT
- PSMA
- PGDS
Microbiology微生物
- Bacterial
- Antibiotics
- Anti-infection
- Fungal
- Antiviral
- COVID-19
- Parasite
- Reverse
- Transcriptase
- HIV
- HCV Protease
- HIV Protease
- ribosome
- SARS-CoV
- Influenza Virus
- β-lactamase
- Integrase
- HBV
- CMV
- HCV
- Neuraminidase
- HSV
- Thioredoxin Reductase
- Enterovirus
- RSV
- DprE1
- 3C-Like Protease
- Ribosomal Peptidyl Transferase
- HPV
Others
- Others
- Dyes
- Antineoplastic and Immunosuppressive Antibiotics
- ADC Cytotoxin
- Selection Antibiotics for Transfected Cell
- PROTAC
- Antibiotics for Mammalian Cell Culture
- ADC Linker
- Molecular Glues
- Antibiotics for Plant Cell Culture
- PROTAC Linker
- Hydrotropic Agents
- E3 ligase Ligand
- Target Protein Ligand
- Antibody-Drug Conjugate
- Drug-Linker Conjugates for ADC
- Chelating Agent
- Surfactant
- Enzyme Substrate

Nab-Paclitaxel 白蛋白紫杉醇目录号D8001068 请避光密封保存！

￥680.00

Paclitaxel，PTX, Taxol, Onxal,紫杉醇（CAS#33069-62-4 目录号D801150）

￥535.00

Ferrostatin-1 (Fer-1) ,铁抑素-1（CAS#347174-05-4 目录号D807243）

￥450.00

DPPH ，1,1-二苯基-2-三硝基苯肼（DPPH）（CAS#1898-66-4 目录号D919475）

￥762.00

5-Azacytidine (5-Aza, Azacitidine),别名:5-Azacytidine, 5-AzaC,Ladakamycin, AZA,5-Aza, CC-486,NSC 102816, 中文名：氮胞苷, 5-氮胞苷 CAS#320-67-2 目录号#D801782

￥530.00

MS417,GTPL7512,BRD4抑制剂（CAS#916489-36-6 目录号D931881）

￥870.00

Torin 1 mTORC1/2抑制剂（CAS#1222998-36-8 目录号D910131）

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